(888)721-2121

PO Box 12054 RTP, NC 27709, USA

Attagene is a life science company, located in Research Triangle Park, NC, that has been transforming drug development and toxicity testing since 2001. Attagene has developed and patented a first-of-a-kind technology, FACTORIAL™ that enables high-content assessment of multiple gene regulatory pathways in live cells. A distinct feature of the FACTORIAL� platform is that it allows simultaneous assessment of multiple endpoints in a single well of cells, thereby eliminating intra-assay variations and producing robust and highly reproducible activity profiles.

Using the FACTORIAL™ platform, we constructed a family of assays that enable quantitative assessments of activities of multiple transcription factors (TFs) and nuclear receptors (NRs) in various cell systems.

• The TF FACTORIAL™ (a.k.a. cis-FACTORIAL�) assay affords profiling activities of over 90 TFs in human and animal cells.
• The Multireporter Mouse™ is an embodiment of the TF FACTORIAL™ allowing profiling activities of multiple TFs in the mouse liver.
• The NR FACTORIAL™ (a.k.a. trans-FACTORIAL) enables assessing agonist/antagonist activities of compounds against all 48 human NRs.